KMID : 1103720100630020177
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Journal of the Korean Society of Radiology 2010 Volume.63 No. 2 p.177 ~ p.183
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Modified Classification of MRI Findings to Predict Histologic Grading of Liposarcomas
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Moon Tae-Yong
Lee In-Sook Hwang In-Kyung Yang Ik Lee Sun-Joo Choi Yoon-Young
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Abstract
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Purpose: To predict the histopathologic grading of liposarcomas with the modified classification of MRI findings.
Materials and Methods: The 47 MRI studies of pathologically confirmed liposarcomas were retrospectively analyzed, and found to have well-differentiated (n=17) and myxoid (n=16) types, representing the ¡¯low grade¡¯ sarcomas, as well as the round cell (n=9) and pleomorphic (n=5) types, which represent the ¡¯high grade¡¯ sarcomas. The MRI findings of liposarcomas were classified into four groups as the one with fat signal above 80%, 20-80%, below 20%, and no fat signal on T1-weighted images (WIs), into three groups as the one with high signals with reticular or irregular lines, homogeneous above 50% of the area, and heterogeneous above 50% on the T2WIs, and into three groups as the one enhanced with reticular or irregular lines and enhancement areas above 50% and below 50% on the Gd-DTPA T1WIs.
Results: The sarcomas with a lower amount of fat signals on T1WIs had a significantly higher histologic grade (p = 0.026) and also showed heterogeneous high signals above 50% on the T2WIs was statistically significant difference (p =0.010) but not on the contrast enhanced T1WIs (p = 0.070).
Conclusion: The modified classification of the MR findings could help predict the histologic grading of liposarcomas.
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KEYWORD
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Liposarcoma, Soft Tissue Neoplasms, Magnetic Resonance Imaging, Classification
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